A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …

The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …

The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-binding
domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient plasma. Little …

We have identified a unique case of acute promyelocytic leukaemia (APL) with at(11;17)
reciprocal chromosomal translocation involving the retinoic acid receptor alpha (RAR alpha) …

Development of multidrug resistance in cancer cells and adverse side effects are the major
obstacles for effective cancer chemotherapy.[1-3] Therapeutic strategies to overcome drug …

The ability of the immune system to eliminate and shape the immunogenicity of tumours
defines the process of cancer immunoediting 1 . Immunotherapies such as those that target …

Using effective temperature and metallicity derived from SDSS spectra for∼ 60,000 F-and G-type
main-sequence stars (0.2< gr< 0.6), we develop polynomial models for estimating …

Wound healing impairment represents a particularly challenging clinical problem to which
no efficacious treatment regimens currently exist. The factors ensuring appropriate …

Curcumin is a naturally occurring poly-phenolic compound with a broad range of favorable
biological functions including anti-cancer, anti-oxidant and anti-inflammatory activities. The …

Background— Essential hypertension has been recognized as a disease resulting from a
combination of environmental and genetic factors. Recent studies demonstrated that …