User profiles for B. Iben

thierry biben

Université de Lyon
Verified email at univ-lyon1.fr
Cited by 4836

Homeodomain factor Nkx2-5 in heart development and disease

RP Harvey, D Lai, D Elliott, C Biben… - Cold Spring Harbor …, 2002 - symposium.cshlp.org
… 2a,b). Progenitors then begin to express cardiac transcription factors such as GATA4/5/6,
Nkx2-5, Mef2B/C, and Tbx5/20, and a primitive myogenic program is activated (Harvey 2002a). …

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

F Sierro, C Biben, L Martínez-Muñoz… - Proceedings of the …, 2007 - National Acad Sciences
… We generated Cxcr7 −/− mice but found that CXCR7 deficiency had little effect on B cell …
PCR in human (B) and murine (C) T and B cells relative to naive or follicular (FO) B cells, …

Chamber formation and morphogenesis in the developing mammalian heart

…, WH Lamers, ZZ Bao, S Palmer, C Biben… - Developmental …, 2000 - Elsevier
… (B–D) The gene for Tbx5 is expressed in the cardiac crescent of E8 (B) and in the linear heart
of E8.5 (C) embryos, in an anteroposterior gradient. This gradient is essentially unchanged …

[HTML][HTML] An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation

…, Y Watanabe, S Zaffran, F Bajolle, C Biben… - Cell, 2007 - cell.com
During heart development the second heart field (SHF) provides progenitor cells for most
cardiomyocytes and expresses the homeodomain factor Nkx2-5. We now show that feedback …

NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

…, K Koutsis, ES Ng, R Jenny, EL Lagerqvist, C Biben… - Nature …, 2011 - nature.com
NKX2-5 is expressed in the heart throughout life. We targeted eGFP sequences to the NKX2-5
locus of human embryonic stem cells (hESCs); NKX2-5 eGFP/w hESCs facilitate …

[PDF][PDF] Adult cardiac-resident MSC-like stem cells with a proepicardial origin

…, MK Menon, CJ Scarlett, A Rashidianfar, C Biben… - Cell stem cell, 2011 - cell.com
… clonogenic cells that could also give rise to the spectrum of colony types (Figure S1A), but
were capable of only slow and short-term growth ($2 months; four passages; Figure 1B) and …

Cardiac Septal and Valvular Dysmorphogenesis in Mice Heterozygous for Mutations in the Homeobox Gene Nkx2-5

C Biben, R Weber, S Kesteven, E Stanley… - Circulation …, 2000 - Am Heart Assoc
Heterozygous mutations in the cardiac homeobox gene, NKX2-5, underlie familial cases of
atrial septal defect (ASD) with severe atrioventricular conduction block. In this study, mice …

Phase-field approach to three-dimensional vesicle dynamics

T Biben, K Kassner, C Misbah - Physical Review E, 2005 - APS
… B1–B3 in Appendix B. The vectors of the reciprocal basis are given by Ei=gijEj see expression
B4 in Appendix B; we use the Einstein summation convention throughout. We are now in …

Phase separation of asymmetric binary hard-sphere fluids

T Biben, JP Hansen - Physical review letters, 1991 - APS
On the basis of thermodynamically self-consistent integral equations for the pair structure it
is shown that dense binary mixtures of hard spheres, of diameters σ 1 and σ 2, phase …

Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development.

C Biben, RP Harvey - Genes & development, 1997 - genesdev.cshlp.org
One of the first morphological manifestations of left/right (L/R) asymmetry in mammalian
embryos is a pronounced rightward looping of the linear heart tube. The direction of looping is …