Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast-to-hyphal
transition of Candida albicans, a key virulence trait of this important human fungal …

Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically
significant roles. THP is a precursor in the production of the drugs atracurium and cisatracurium, …

Grass pea (Lathyrus sativus L.) is a rich source of protein cultivated as an insurance crop in
Ethiopia, Eritrea, India, Bangladesh, and Nepal. Its resilience to both drought and flooding …

Plant halogenated natural products are rare and harbor various interesting bioactivities, yet
the biochemical basis for the involved halogenation chemistry is unknown. While a handful …

Plants contain rapidly evolving specialized enzymes that support the biosynthesis of
functionally diverse natural products. In coumarin biosynthesis, a BAHD acyltransferase-family …

Background Characterization of the skin and wound microbiome is of high biomedical interest,
but is hampered by the low biomass of typical samples. While sample preparation from …

Genome‐wide association studies (GWAS) are an effective approach to identify new specialized
metabolites and the genes involved in their biosynthesis and regulation. In this study, …

Background There is a need to develop biomarkers for diagnosis and prediction of treatment
responses in depression and post‐traumatic stress disorder (PTSD). Methods Cross‐…

The mRNA for the Duffy blood group antigen, the erythrocyte receptor for the Plasmodium
vivax malaria parasite, has recently been cloned and shown to encode a widely expressed …

Global insights into cellular organization and genome function require comprehensive
understanding of the interactome networks that mediate genotype–phenotype relationships 1 , 2 . …