Tumorigenesis is dependent on the reprogramming of cellular metabolism as both direct and
indirect consequence of oncogenic mutations. A common feature of cancer cell metabolism …

Metabolism of cancer cells is geared toward biomass production and proliferation. Since the
metabolic resources within the local tissue are finite, this can lead to nutrient depletion and …

Biochemistry textbooks and cell culture experiments seem to be telling us two different
things about the significance of external glutamine supply for mammalian cell growth and …

The rapid retreat and thinning of the Arctic sea ice cover over the past several decades is
one of the most striking manifestations of global climate change. Previous research revealed …

Lactic acid-producing bacteria are associated with various plant and animal niches and
play a key role in the production of fermented foods and beverages. We report nine genome …

Adult hippocampal neurogenesis declines in aging rodents and primates. Aging humans
are thought to exhibit waning neurogenesis and exercise-induced angiogenesis, with a …

Recent developments in photonic technology provide the ability to noninvasively image cells
in vivo; these new cellular imaging technologies have the potential to dramatically improve …

The mechanical mismatch between soft neural tissues and stiff neural implants hinders the
long-term performance of implantable neuroprostheses. Here, we designed and fabricated …

OBJECTIVE Short sleep duration is associated with impaired glucose tolerance and an
increased risk of diabetes. The effects of sleep restriction on insulin sensitivity have not been …

Brown adipose tissue (BAT) dissipates chemical energy and generates heat to protect animals
from cold and obesity. Rodents possess two types of UCP-1 positive brown adipocytes …