The capacity to fine-tune cellular bioenergetics with the demands of stem-cell maintenance
and regeneration is central to normal development and ageing, and to organismal survival …

Tumor maintenance relies on continued activity of driver oncogenes, although their rate-limiting
role is highly context dependent. Oncogenic Kras mutation is the signature event in …

We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …

We find that on average, an announcement of rising unemployment is good news for stocks
during economic expansions and bad news during economic contractions. Unemployment …

The poor mechanical properties remain the largest barrier to traditional synthetic hydrogels
for extensive practical applications, such as tissue scaffolds. In this work, we have …

Objective The SARS-CoV-2-infected disease (COVID-19) outbreak is a major threat to human
beings. Previous studies mainly focused on Wuhan and typical symptoms. We analysed …

Conventional metals become harder with decreasing grain sizes, following the classical Hall-Petch
relationship. However, this relationship fails and softening occurs at some grain sizes …

Ionogels are compelling materials for technological devices due to their excellent ionic
conductivity, thermal and electrochemical stability, and non-volatility. However, most existing …

Recent advances in spatially resolved transcriptomics (SRT) technologies have enabled
comprehensive characterization of gene expression patterns in the context of tissue …

Two contrasting intrusive suites have been identified from the northern margin of the North
China craton: a Late Carboniferous dioritegranodiorite suite mainly made up of quartz diorite, …